Cancer drug delivery and brain tumor-specific drug delivery are major application of sustained release coating
Sustained Release Coating |
Sustained release coating are
used in the pharmaceutical industry for the controlled release of medications.
Among the most popular applications are cancer drug delivery and brain
tumor-specific drug delivery. Currently, tablets are the most popular form of
sustained release coatings, accounting for the majority of the market. However,
mini-tablets have several advantages over traditional forms, such as low
production cost, less inter-subject variability, and reduced dosage dumping.
Additionally, mini-tablets are an excellent formulation for modified-release
tablets. These products are becoming increasingly popular and will be available
in the market soon.
The Global
Sustained Release Coating Market is estimated to be valued at US$ 508.2 Mn in 2021 and is
expected to exhibit a CAGR of 6.6%
over the forecast period (2021-2028).
While there are many other types
of sustained-release coating materials, ethyl & methylcellulose are the
most common. The primary mechanism of release is drug diffusion across a
water-insoluble membrane. Moreover, this coating material is used in both
sustained-release and moisture barrier applications. Additionally, it has
taste-masking capabilities. In short, a sustained-release coating offers
multiple advantages over conventional formulations.
The development of a new
formulation for this type of drug delivery system has also enabled the
development of an entirely new form of a pharmaceutical product. In a recent
study, a polymer composition comprising a combination of ethyl cellulose and
magnesium silicate was developed. These polymers were sprayed into the beads.
These particles were coated in a suitable solvent to enhance their release
properties. They were successfully tested and approved, and the formulation is
suitable for a variety of applications. This new formulation also features
pH-insensitive properties, which are desirable for sustained-release drug
delivery. Further, it is a promising candidate for the development of
sustained-release coatings for oral dosage forms. These coatings induced the
release of a model drug, chloramphenicol. The results were impressive, and the
study also revealed that ethyl cellulose polymer has a qualitative and
quantitative effect on drug release.
Comments
Post a Comment