What is angiosarcomas? What are the various angiosarcomas treatment available today?
Angiosarcomas tend to invade
adjacent tissue and therefore, complete excision is challenging. To improve
Angiosarcomas treatment outcomes, some studies have used a multimodality
approach, combining surgery, radiation therapy, and chemotherapy. In a recent
retrospective study, 55 patients with angiosarcoma of the face underwent
chemotherapy, radiation therapy, or a combination of these treatments. Patients
who received multimodality therapy had a favorable response rate to
local-regional control and longer overall survival.
According to Coherent Market Insights the Angiosarcomas
Treatment Market Global Industry Insights, Trends, Outlook, and
Opportunity Analysis, 2022-2028.
Molecular markers are a common
way to detect angiosarcoma. CD31, CD34, factor VIII-related antigen (Fli-1),
and ERG are markers that are specific for this cancer. Positive results in any
one of these markers may be helpful in distinguishing between epithelioid and
non-epithelioid angiosarcomas. In addition to standard markers, several ongoing
studies focus on identifying specific genetic alterations and molecular markers
that may be associated with angiosarcoma.
The most common angiosarcoma
treatment is surgery. This procedure removes the tumor and surrounding healthy
tissue and may be followed by radiotherapy. If the tumor is too large, surgery
is not a viable option. However, this type of treatment is effective for small
angiosarcomas that do not spread widely. In addition to surgery, some doctors
also use radiation therapy around the surgical site to prevent the tumor from
growing after it is removed. Early diagnosis is essential to reduce the risk of
recurrence or death. There are various diagnostic tests for angiosarcoma, but
the most effective way to find the disease is to perform a physical exam. It
will be helpful to know the risk factors before starting treatment. Standard
treatment consists of surgery, radiation therapy, and chemotherapy. However,
the results of treatment are dependent on tumor site, size, and resectability.
In addition, some studies have shown that targeted medicines and immunotherapy
have the potential as treatments for angiosarcomas.
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