Anticonvulsant is one of the Common Drug Used in Childhood Absence Epilepsy Treatment

 

Childhood Absence Epilepsy Treatment 

Childhood absence epilepsy is a condition in which a child experiences seizures without an aura. The seizures are typically brief and occur in conjunction with behavioral arrest, eyelid fluttering, and hand automatisms. Children with this condition usually experience their first seizure when they are around three years old. The duration of a typical absence seizure is nine to fourteen seconds, although the exact duration of a seizure can vary.

The typical electroencephalogram (EEG) shows generalized spike and wave discharges at frequencies ranging from three to 4.5 Hz. Moreover, the frequency of the EEG decreases gradually from the time of onset to the time of termination, indicating that the seizure is a generalized one. Although the EEG is not synchronous, it is clinically useful to evaluate the frequency of these occurrences in children.

The Global Childhood Absence Epilepsy Treatment Market was valued at US$ 158.2 million in 2017 and is expected to witness a robust CAGR of 5.4% over the forecast period (2018 – 2026).

The diagnosis of CAE requires the evaluation of underlying conditions. The symptoms and prognosis of the disorder can be characterized by the presence or absence of brain lesions. Some treatment options for CAE include a combination of topiramate and lamotrigine. Besides these, a ketogenic diet is also helpful for children with this disorder.

Childhood absence epilepsy can lead to learning disabilities and cognitive impairments. However, the child may experience a normal development and learning process as long as the seizures are well-controlled. The child with CAE will usually recover from these problems by the time they reach adolescence. Childhood absence epilepsy treatment includes anticonvulsant drugs. Ethosuximide and valproic acid are the other childhood absence epilepsy treatment of choice. However, there is little research on the pharmacological-resistant forms of the disorder and the neuropsychological consequences for affected children. Childhood absence epilepsy is viewed as a serious condition, and future studies need to look at the comorbidities and potential resistance to conventional therapy.