Blood Irradiator; Used To Prevent Rare But Serious Complication of Blood Transfusions

 

Blood Irradiator
Blood Irradiator 

Blood irradiator is a life-saving technology that prevents graft-versus-host disease associated with blood transfusions, a condition that can be fatal for blood transfusion recipients with compromised immune systems. Blood irradiation is a therapy in which blood components are irradiated prior to transfusion, to prevent proliferation of certain types of T lymphocytes. It is an alternative medical procedure in which the blood is exposed to low level light (often laser light) for therapeutic reasons.

According to Coherent Market insights the Blood Irradiator Market Size, Share, Outlook, and Opportunity Analysis, 2022-2028

These medical devices are extensively used in blood banks and hospitals for blood irradiation and for clinical and research purposes, such as in cancer research and for blood transfusion. Blood irradiation is necessary for those who are at risk for graft versus host disease, including individuals receiving platelets, patients undergoing hematopoietic transplantation, and fetuses receiving intrauterine transfusions. Blood irradiator is used to expose a wide range of samples to gamma radiation for a variety of purposes.

Irradiation of blood & blood products by gamma rays is a proven and safe method eliminate the risk of post transfusion graft versus host disease Gamma Irradiation Chambers are also used extensively in academic institutions for research and analysis. Irradiated blood is often used to prevent a very rare but serious complication of blood transfusions called 'transfusion-associated graft-versus-host disease', in which lymphocytes from transfused blood component attack the recipient's tissues, especially the skin, bone marrow, and gastrointestinal tract.

Gamma irradiation of blood products has been the mainstay of TA-GVHD prevention. Japan uses universal irradiation of all labile blood components, as a higher rate of TA-GvHD has been reported due to common HLA tissue types. The Japan Society of Transfusion Medicine and Cell Therapy issued first guidelines on the irradiation of blood and blood components to prevent PT-GVHD in 1992, and issued the fifth version of the guidelines in 2010.

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