Alkaline Proteases Are Widely Used In Detergent Industry for Detergent Additives, Peptide Synthesis and Leather Processing

Alkaline Proteases 

Microbial proteases are categorized into several categories, depending on their pH range and active site groups (metallo-, aspartic-, cysteine- or sulphydryl-, or serine-type). They have been used for various applications such as bioremediation of soils, sewage treatment, food production, animal feed production, enzyme-aided polymerization of polyurethane and phenolics, and textile and fiber processing.

Microbial alkaline proteases are enzymes active in a neutral to alkaline pH range. They are mainly found in Bacillus bacteria and other gram-negative bacteria such as Pseudomonas17, Xanthomonas18, and Vibrio19. They are also found in fungi. According to Coherent Market Insights the Alkaline Proteases Market Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2022-2028.

Proteases are enzymes that catalyze the hydrolysis of the peptide bonds between proteins. They are a vital component of detergent production and have several industrial applications such as food, pharmaceutical, and leather processing. They are also used in bioremediation to control environmental pollution. Alkaline Proteases have a high demand in the detergent industry for detergent additives, peptide synthesis, and leather processing. They are also useful in a variety of other industries including textile, photography, silk degumming, and waste management.

They can be isolated from a wide variety of microorganisms, especially those that are capable of growing at low temperatures. However, their optimum temperature requirements vary widely among microorganisms and must be carefully controlled during culture development to achieve maximum enzyme production.

Besides temperature, other important parameters that must be controlled during cultivation include medium pH, protein concentration, metal requirement and reactivity. The optimum pH for enzyme production is generally in the range of 6.5-8.0. Moreover, metal ions such as Hg2+ or Pb2+ can inhibit the activity of these enzymes by affecting their organic ligand binding, thereby reducing their thermotolerance. The optimum temperature for alkaline protease production by different microorganisms is varied significantly and must be closely monitored during culture development. Ideally, the temperature should be kept above 30 deg C to ensure maximum enzyme production. Recently in January 2020, Specialists Supplements introduced GreeNourish complete a blend of organic superfoods that consists of papain, bromelain, and other nutrients for improving body functions and health at cellular level.