Antibody Drug Conjugates; Drugs Designed As a Targeted Therapy for Treating Cancer

 

Antibody Drug Conjugates Market
Antibody Drug Conjugates

Antibody drug conjugates (ADCs) are a new class of highly potent therapeutics. They combine a monoclonal antibody (mAb) with an antigen to target cancer cells. Antibody drug conjugates are a class of drugs designed to treat cancer. ADC is a type of cancer therapy that uses an antibody to target cancer cells. The conjugated drug is usually made up of a monoclonal antibody linked to a small molecule that is stable in water. ADCs are designed to target cancer cells and are approved by the U.S. Food and Drug Administration (FDA).

The Global Antibody Drug Conjugates Market is estimated to be valued at US$ 4.29 Bn in 2021, and is expected to exhibit a CAGR of 14.0% over the forecast period (2021-2028).

As of June 2022, the FDA has approved 12 ADC cancer therapies, (ado-trastuzumab emtansine (Kadcyla), brentuximab vedotin (Adcetris), inotuzumab ozogamicin (Besponsa), gemtuzumab ozogamicin (Mylotarg), Moxetumomab pasudotox (Lumoxiti), Enfortumab vedotin (Padcev), Sacituzumab govitecan (Trodelvy), Trastuzumab deruxtecan (Enhertu), polatuzumab vedotin-piiq (Polivy), belantamab mafodotin-blmf (Blenrep), loncastuximab tesirine-lpyl (ZYNLONTA), and tisotumab vedotin-tftv (Tivdak), 5 for solid tumors and 7 for hematological malignancies.

There are 12 FDA approved Antibody Drug Conjugates and multiple clinical trials. They can be used in combination with other drugs and are increasingly being investigated for use in cancer treatment. Antibody drug conjugates are highly specific cancer therapeutics work by targeting cancer cells with monoclonal antibody. These complex molecules are linked to a cytotoxic drug, which then directs itself to tumor cells overexpressing the target. The combination of antigen-specificity and potency makes ADCs an excellent choice for a number of applications.

Antibody Drug Conjugates (ADCs) are drugs designed to target specific cancer cells and release a toxic drug into the cancer cell. ADCs are generally well tolerated with few predictable adverse reactions as well as new medical issues that need careful approach. In short, ADCs are a promising cancer treatment and show promise in the development of effective cancer therapies.

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